• Why ChemoFx^®?
• Commitment to clinical proof
• ChemoFx^®
  clinical trials
• Indications & use
• Specimen handling
• Interpretation
  of results

ChemoFx^® was designed to show chemotherapy resistance and sensitivity over a broad range of agents and tumor types, including ovarian, breast, endometrial, cervical, lung and colorectal.* With its broad range of uses, ChemoFx^® can be advantageous to a large population of patients—including yours. In addition to its range, it can also be used to provide guidance during several stages of your patient's care. Where we've seen this used most frequently in clinical practice is:

• during initial surgery
• when there are known toxicities to Standard of Care therapy
• when patient is refractory to initial treatment
• when the particular tumor type has no established protocol
• when patient presents with recurrent cancer

*Leukemia and lymphoma are not tested at present.

ChemoFx^® makes it easy to determine the chemotherapy that is most likely to be effective for your particular patient. Find the proper instructions below based on your role in the treatment process.

In-office process
1. Mark “Send to Precision Therapeutics for ChemoFx^®” on physician order
2. For standing orders, call to inform your Precision Therapeutics sales rep that a specimen will be sent for ChemoFx^® testing
3. Provide your patient with the ChemoFx^® patient brochure explaining their role in the process


Operating room process
1. Ensure specimen cup (without formalin) or ChemoFx^® shipping container is available prior to surgery
2. Collect tissue specimen
1. If sending tissue directly to Precision Therapeutics from operating room, collect specimen no smaller than 35 mg and no larger than 1g. Package specimen according to instructions in ChemoFx^® shipping container
2. If sending tissue to pathology, mark “Send to Precision Therapeutics for ChemoFx^®” and immediately transport to lab




Interventional radiology process
Core Biopsy
1. Ensure specimen cup (without formalin) or ChemoFx^® shipping container is available prior to biopsy
2. Collect biopsies
1. If sending tissue directly to Precision Therapeutics, provide the recommended number of biopsies and package specimen according to instructions:
• 14g needle; ship a minimum of 2 cores
• 16g needle; ship a minimum of 3 cores
• 18g needle; ship a minimum of 4 cores
2. If sending tissue to pathology, mark “Send to Precision Therapeutics for ChemoFx^®” and immediately transport to lab




Fluid
1. Ensure evacuated container or ChemoFx^® shipping container is available prior to procedure
2. Collect fluid specimen
1. If sending fluid directly to Precision Therapeutics, collect specimen no less than 100 cc and no larger than 500 cc. Package specimen according to instructions in ChemoFx^® shipping container
2. If sending fluid to pathology, mark “Send to Precision Therapeutics for ChemoFx^®” and immediately transport to lab


Pathology Process
1. Transfer tissue or fluid specimen to ChemoFx^®-supplied specimen vial or fluid bottle
1. 35 mg minimum tissue specimen, 1 g maximum
2. 100 cc minimum fluid specimen, 500 cc maximum
2. Package specimen as quickly as possible after arrival and follow instructions in ChemoFx^® shipping container