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• Commitment to clinical proof
• ChemoFx^®
  clinical trials
• Indications & use
• Specimen handling
• Interpretation
  of results
• Precision Therapeutics
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In 8 to 10% of cases, testing cannot be completed because of poor sampling. You can reduce that possibility by following these simple instructions:

• Do not spin down, freeze or put tissue in formalin
• Send sample as soon as possible after extraction (within 24 hours). Samples received more than 5 days after extraction are not accepted
• Keep sample as sterile as possible
• Follow packaging procedures carefully
• Submit the order form in a timely manner
• Contact your Precision Therapeutics Client Services representative to arrange for pick-up

How to prepare solid tissue specimen
Surgical specimens:
1. Select solid, viable specimen.
• If necessary, trim visible necrotic and adipose tissue using sterile technique.
• Minimum size is 35 mg; maximum size is 1 g (suggested size = size of nickel).
2. Place specimen into collection vial.
Biopsy specimens:
1. Extract biopsies.
• For core biopsies, recommended number of cores:
• 14g needle; ship a minimum of 2 cores
• 16g needle; ship a minimum of 3 cores
• 18g needle; ship a minimum of 4 cores
• For vacuum-assisted biopsies, submit 1-2 biopsies
2. Place biopsies into collection vial.
How to package solid tissue specimen
1. Complete the Tumor Transport Requisition and Patient Identification Label;
   place label on vial.
2. Place vial into biohazard bag between cold packs. Squeeze out excess air and seal.
3. Place bagged vial into the foil bag and seal.
4. Place foil bag in box. Close box. (Ensure that all Protected Health Information [PHI]
   is inside box)
5. Affix airbill on FedEx bag and place box into bag. Refrigerate until pickup.
6. Call Precision Therapeutics at 1-800-547-6165 and provide tracking information.

How to prepare regular fluid specimen
1. Remove the Precision-labeled empty sterile bottle from the collection container.
2. Complete the Tumor Transport Requisition and Patient Identification Label.
3. Peel and place completed label on bottle; place completed Tumor Transport Requisition inside box.
4. Collect fluid specimen. (Suggested amount of fluid is 250 cc but any amount accepted.)
5. Cap bottle securely.
6. Place specimen bottle into biohazard bag between cold packs. Squeeze out excess air and seal.
7. Place bagged bottle into the foil bag and seal.
8. Place foil bag inside box. Close box. (Ensure that all Protected Health Information [PHI] is inside box)
9. Affix FedEx airbill on FedEx bag and place box into bag. Refrigerate until pickup.
10. Call Precision Therapeutics at 1-800-547-6165 and provide package tracking information.

How to prepare vacuum-assisted fluid specimen
1. Remove the empty 500 cc glass bottle from the collection container (or use your own bottle).
2. Complete the Tumor Transport Requisition and Patient Identification Label.
3. Peel and place completed label on bottle; place completed Tumor Transport Requisition inside box.
4. Collect fluid specimen. (Suggested amount is 100-500 cc but any amount accepted.)
5. Place bottle into biohazard bag between cold packs. Squeeze out excess air and seal.
6. Place bagged bottle into the foil bag between cold packs and seal.
7. Place foil bag inside box. Close box. (Ensure that all Protected Health Information [PHI] is inside box)
8. Affix FedEx airbill on FedEx bag and place box into bag. Refrigerate until pickup.
9. Call Precision Therapeutics at 1-800-547-6165 and provide package tracking information.